Proteomic and immunohistochemical signatures of neuroendocrine tumours
Research type
Research Study
Full title
Proteomic and immunohistochemical signatures of neuroendocrine tumours
IRAS ID
155954
Contact name
Alberto Quaglia
Contact email
Sponsor organisation
King's College Hospital NHS Foundation Trust
Duration of Study in the UK
6 years, 11 months, 30 days
Research summary
This project aims to identify strategies that can be used to individualise the clinical care of patients with neuroendocrine tumours (NETs).
Neuroendocrine tumours (NETs) are increasing in prevalence and incidence. The cause for this remains unclear. NETs have been historically regarded as indolent malignancies with individuals presenting late with advanced stage disease.
This study will explore personalised medicine strategies through analysis of tissue to help improve NET disease modelling.
Samples will be analysed using a variety of techniques, including proteomic, histological and immunohistochemical methods, to identify critical factors that affect disease course, treatment response and clinical outcomes.
Identifying differences or patterns in tissue would hopefully aid with the development of personalised treatment strategies that improve clinical and patient outcomes.
REC name
London - Central Research Ethics Committee
REC reference
14/LO/1867
Date of REC Opinion
13 Oct 2014
REC opinion
Favourable Opinion