Prostate Extracellular Vesicle Isolation (PEVI)

• Research type

  Research Study

• Full title

  An Investigation into the use of Extracellular Vesicle Isolation and Analysis of Urine Samples in the Detection of Prostate Cancer

• IRAS ID

  299344

• Contact name

  Nikhil Vasdev

• Contact email

  nikhil.vasdev@nhs.net

• Sponsor organisation

  East & North Hertfordshire Hospitals NHS Trust

• Duration of Study in the UK

  1 years, 2 months, 10 days

• Research summary

  Prostate cancer screening and investigations are usually initiated by the use of a prostate specific antigen (PSA) blood test. This is a low sensitivity test performed that can help identify patients that require further investigation for prostate cancer. Following this, MRI and prostate biopsies are required to identify or exclude cancer diagnosis. Due to PSA’s low sensitivity, a proportion of patients undergo these investigations unnecessarily. Additional more sensitive tests may help reduce the number of unnecessary tests performed.
  This study will seeks to prove how urinary analysis will prove invaluable in helping to diagnose prostate cancer through non – invasive means and possibly hold the key to future diagnosis.

• REC name

  London - City & East Research Ethics Committee

• REC reference

  21/PR/0819

• Date of REC Opinion

  20 Aug 2021

• REC opinion

  Further Information Favourable Opinion