Prospective evaluation of AI-ECG for SHD detection
Research type
Research Study
Full title
Prospective evaluation of artificial intelligence-enhanced electrocardiography for detection of structural heart disease
IRAS ID
353515
Contact name
Fu Siong Ng
Contact email
Sponsor organisation
Imperial College London
Clinicaltrials.gov Identifier
179372, Sponsor reference number
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
This study aims to improve the early detection of undiagnosed heart disease, which causes serious health issues, hospital admissions, and high healthcare costs. Researchers are exploring how artificial intelligence (AI) can analyse routine heart tests, called electrocardiograms (ECGs), to detect heart problems. These tests can be done using both traditional ECG machines and portable, wearable devices like smartwatches, making it easier for people to monitor their heart health at home.
While AI has shown promise using past data, this study will involve the collection of ECG data and subsequent testing of its accuracy in real-world settings to ensure it works well for both doctors and patients. The goal is to see if AI can identify conditions like heart muscle weakness, valve issues, and high lung pressure from the ECG data of patients. The researchers will also compare AI’s detections with other blood tests commonly used to diagnose heart disease.
The AI models that will be used are being tested for research and validation purposes only. They will not be used for clinical decision-making or providing information to influence diagnosis, treatment, or patient care during the study. The AI outputs are not shared with clinicians and will have no impact on the care pathway.
This research will demonstrate if AI-powered ECG analysis - whether from traditional or portable devices - can provide a low-cost, non-invasive way to detect heart disease early and improve health assessments.
REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
25/EM/0166
Date of REC Opinion
16 Jul 2025
REC opinion
Further Information Favourable Opinion