PROSPECT

  • Research type

    Research Study

  • Full title

    Validation of new Prognostic biomarkerRs in patients with cirrhOsis diScharged after a hosPitalization due to acutE deCompensation or acuTe-on-chronic liver failure

  • IRAS ID

    357265

  • Contact name

    Rajeshwar Mookerjee

  • Contact email

    r.mookerjee@ucl.ac.uk

  • Sponsor organisation

    EF-CLIF

  • ISRCTN Number

    ISRCTN00000000

  • Clinicaltrials.gov Identifier

    NCT00000000

  • Duration of Study in the UK

    1 years, 7 months, 1 days

  • Research summary

    Multicenter prospective observational study.
    The study is conducted in 9 European clinical centers: 3 in Spain, 2 in Italy and Germany, 1 in France and 1 in United Kingdom.
    The clinical trial comprises 189 participants and will be conducted to test the prognostic accuracy of novel biomarkers identified within the DECISION project.. This trial will include participants discharged from the hospital after a hospitalization due to development of specific, cirrhosis-related complications, associated with re-admissions and poor outcomes.
    Participants will be treated according to routine clinical practice, and will be followed up until 6 months after the enrollment in the study.

  • REC name

    London - London Bridge Research Ethics Committee

  • REC reference

    25/LO/0400

  • Date of REC Opinion

    11 Jul 2025

  • REC opinion

    Further Information Favourable Opinion