PROSPECT
Research type
Research Study
Full title
PROgnosiS Prediction after Enhanced or CriTical care
IRAS ID
346848
Contact name
Sarah Vollam
Contact email
Sponsor organisation
University of Oxford/Research Governance, Ethics & Assurance team
Duration of Study in the UK
2 years, 6 months, 30 days
Research summary
Every year in the United Kingdom 1 in 10 (14,000) people discharged from an Intensive Care Unit (ICU) die unexpectedly, or urgently return to an ICU before hospital discharge. Of those who leave hospital, a quarter are unexpectedly readmitted within 3 months. It is not known whether additional electronic information about patients discharged from ICU may support critical care follow-up staff to prioritise who to monitor more closely.
This study aims to develop a digital system including wearable monitoring (already established in other in-hospital populations) to find patients who are most likely to deteriorate in the near future, both in their post-ICU in-hospital stay and/or in the early period following hospital discharge.
To do this we will use information from earlier research studies as well as experts in this field to pinpoint which information, such as blood tests, would be most useful to spot people at high risk of deterioration after ICU discharge and then extract this information from historical patient records.
We will ask patients to wear the monitoring system for up to 14 days after discharge from ICU, and for 14 days after discharge from hospital. We will then combine the hospital information with information from the wearable devices to estimate the risk of a patient deteriorating after an ICU admission. These patients could then be monitored more closely.
During the study we will work with clinical staff and patients to understand how best to use the information from this monitoring system in clinical practice in future.REC name
South Central - Hampshire A Research Ethics Committee
REC reference
25/SC/0136
Date of REC Opinion
23 May 2025
REC opinion
Favourable Opinion