PROSO-COPD: Protein, Sarcopenic Obesity, and COPD
Research type
Research Study
Full title
Observational study to explore the relationship between dietary protein intake and the prevalence of sarcopenic obesity in adult female with chronic obstructive pulmonary disease (COPD): A Pilot Study
IRAS ID
351765
Contact name
Baukje de Roos
Contact email
Sponsor organisation
University of Aberdeen and NHS Grampian
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
2-005-25,
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Both sarcopenic obesity and chronic obstructive pulmonary diseases (COPD) are common conditions that mainly affect middle-aged and older adults. Our research has shown that increased dietary intake of total and plant-based protein is associated with a lower risk of sarcopenic obesity, using data from the EPIC Norfolk study. Furthermore, a systematic review and meta-analysis, conducted in our group, showed that having sarcopenic obesity was associated with significantly impaired lung function outcomes. Other research has shown that increased intake of dietary protein leads to a better treatment outcome for respiratory diseases.
The aim of this pilot observational study is to investigate, in more detail, the relationship between the quantity and source of dietary protein intake, the prevalence of sarcopenic obesity, and lung function, in a small cohort of older female participants with COPD. The study will also consider the role of inflammation in relation to sarcopenic obesity and lung function outcomes. This study will help to improve our understanding of the relationship between sarcopenic obesity and lung function outcomes, and how dietary protein intake and inflammation can affect this relationship and each of the outcomes.REC name
West of Scotland REC 1
REC reference
25/WS/0055
Date of REC Opinion
5 Jun 2025
REC opinion
Further Information Favourable Opinion