Prospective longitudinal assessment in a COVID-19 infected cohort
Imperial College London and Imperial College Healthcare NHS Trust
Duration of Study in the UK
2 years, 0 months, 0 days
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is a new rapidly spreading infectious disease with no proven treatment options. The virus causes a spectrum of disease ranging from mild cold-like symptoms to severe lung compromise requiring ventilatory support. Guidance from Public Health England identifies several groups that are at risk of severe disease including the elderly and individuals with chronic lung disease. The mechanisms driving severity of disease in these groups of individuals infected with COVID-19 are however poorly understood. We urgently need to understand the reasons for susceptibility to severe infection in these large groups of individuals to facilitate rapid development of novel effective targeted therapies.
South Central - Oxford A Research Ethics Committee
Date of REC Opinion
11 May 2020