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PROSAIC-19 [COVID-19]

  • Research type

    Research Study

  • Full title

    Prospective longitudinal assessment in a COVID-19 infected cohort

  • IRAS ID

    282739

  • Contact name

    Peter Kelleher

  • Contact email

    p.kelleher@imperial.ac.uk

  • Sponsor organisation

    Imperial College London and Imperial College Healthcare NHS Trust

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is a new rapidly spreading infectious disease with no proven treatment options. The virus causes a spectrum of disease ranging from mild cold-like symptoms to severe lung compromise requiring ventilatory support. Guidance from Public Health England identifies several groups that are at risk of severe disease including the elderly and individuals with chronic lung disease. The mechanisms driving severity of disease in these groups of individuals infected with COVID-19 are however poorly understood. We urgently need to understand the reasons for susceptibility to severe infection in these large groups of individuals to facilitate rapid development of novel effective targeted therapies.

  • REC name

    South Central - Oxford A Research Ethics Committee

  • REC reference

    20/SC/0208

  • Date of REC Opinion

    11 May 2020

  • REC opinion

    Favourable Opinion