PROMS and QOL in Pancreatic cancer
Research type
Research Study
Full title
Prospective evaluation of Patient Related Outcome Measures (PROMS) and Health Related Quality of life (HRQoL) in patients with pancreatic cancer
IRAS ID
286774
Contact name
Sanjay Pandanaboyana
Contact email
Sponsor organisation
Newcastle upon tyne hospitals NHS Trust
Clinicaltrials.gov Identifier
09598, NJRO R&D number
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Pancreatic cancer is an aggressive cancer with poor survival. For those patients suitable for surgical intervention, the postoperative complication rates are high. The short survival and higher complication rate have a significant impact on quality of life. Patient related outcome measures are frequently used in cancer surgery to improve quality of care as these patients often have limited survival after morbid and complex treatments therefore requiring careful appraisal and shared decision making. There is lack of data in patients with pancreatic cancer regarding the impact of pancreatic cancer in general and postoperative complications on patient related outcome measures (PROMS). Furthermore, the effect of surgical treatment on PROMS is unknown. This prospective study aims to longitudinally assess PROMS using the core set of patient reported outcomes in pancreatic cancer questionnaire and quality of life (HRQoL) questionnaire (EORTC) QLQ-C30 and the pancreatic cancer module EORTC QLQ-PAN26 for all patients undergoing pancreatic surgery for malignant pathology. The also aims to evaluate the association between postoperative complications and PROMS and HRQoL in the short-term (within 30 days) and long-term (after 3 and 6 months) in order to find out whether and to what extent complications influence the PROMS and HRQOL.
REC name
South Central - Berkshire B Research Ethics Committee
REC reference
20/SC/0359
Date of REC Opinion
21 Oct 2020
REC opinion
Further Information Favourable Opinion