PROMOTE: A Prospective Randomised trial cOMparing embryO developmenT.
Research type
Research Study
Full title
PROMOTE: A Prospective Randomised trial cOmparing embryo Metabolism and develOpmenT in the standard versus the Embryoscope incubator.
IRAS ID
151000
Contact name
Nick S Macklon
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
1 years, 1 months, 30 days
Research summary
This trial examines whether an Embryoscope provides a better environment to culture embryos in as opposed to a traditional MINC benchtop incubator. The Embryoscope allows the developing embryo to be imaged at regular intervals without removing them from the incubator thus providing them with a constant environment. Couples who have more than 6 healthy embryos will be eligible to participate in the study. Half of their embryos will be randomised to the Embryoscope and the other half to the MINC incubator. The embryos will be assessed by examining their structure and form (morphology) and how this changes over time (morphokinetics). In addition to this, we propose to examine the metabolism of the embryos by measuring the concentrations of essential nutrients in the culture medium. This is because it is thought that "quiet" embryos i.e. those who use less nutrients, are in fact more viable.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
14/SC/1260
Date of REC Opinion
3 Nov 2014
REC opinion
Further Information Favourable Opinion