Prognostic tool for LT and resection in patients with HCC

• Research type

  Research Study

• Full title

  Retrospective clinical validation of HepatoPredict, a prognostic tool for hepatic surgery based on a molecular signature.

• IRAS ID

  326619

• Contact name

  Tahir Shah

• Contact email

  tahir.shah@uhb.nhs.uk

• Sponsor organisation

  Ophiomics

• Duration of Study in the UK

  1 years, 4 months, 29 days

• Research summary

  Ophiomics has recently developed HepatoPredict, an innovative medical decision-making prognostic tool aimed at helping physicians and surgeons to select patients with Hepatocellular Carcinoma (HCC) for effective hepatic surgery. This tool does not rely solely on clinical variables but also on tumor expression of a selected set of genes. This in combination with a proprietary algorithm results in a more accurate prediction of patient outcome.
  In this study we aim to validate the effectiveness of this prognostic tool in an independent cohort of patients with early to intermediate HCC who underwent liver transplantation or liver resection.

• REC name

  West Midlands - South Birmingham Research Ethics Committee

• REC reference

  24/WM/0252

• Date of REC Opinion

  29 Jan 2025

• REC opinion

  Further Information Favourable Opinion