Profiling recovery of those discharged into the community with COVID19

  • Research type

    Research Study

  • Full title

    Profiling the determinants of recovery to establish novel rehabilitation guidelines to improve clinically relevant and patient-reported outcomes in the post-COVID-19 period.

  • IRAS ID

    292920

  • Contact name

    Mark Faghy

  • Contact email

    m.faghy@derby.ac.uk

  • Sponsor organisation

    University of Derby

  • Clinicaltrials.gov Identifier

    NCT04649957

  • Duration of Study in the UK

    0 years, 11 months, 14 days

  • Research summary

    Post-acute COVID-19 or ‘long-COVID’ is a colloquial term used to describe patients reporting persistent symptoms and illness for longer periods than are expected and despite clinical resolution [1]. Although the burden of recovery is still in its infancy, the volume of patients requiring support for chronic symptoms is estimated to be >3 million people, creating an unprecedented demand for health care services around the world. In the absence of a vaccine and with the threat of sustained transmission, infections and COVID-19 mutations, there is an urgent need to develop optimised rehabilitation strategies to support patients in the post-COVID period. To date, there are no data that have profiled the time and determinants of a successful and rapid recovery in the post-COVID-19 period. Long-COVID is a complex, multi-system disease associated with a broad range of symptoms including fever, fatigue shortness of breath, chest pain, headaches, neurocognitive difficulties, muscle pains and weakness, depression, and other mental health conditions [2]. Patients who experience, prolonged recovery will require prolonged support and follow ups. The greatest challenge is to support the large volumes of patients with a non-specific clinical picture, >50% of all hospital admissions that are being discharged into community settings with substantial co-morbidities. This project will establish whole patient perspectives that contain multi-method methodologies, objective analysis via longitudinal investigations to document symptom profiles and to establish tailored mechanisms of support for patients recovering in community settings.

  • REC name

    South West - Cornwall & Plymouth Research Ethics Committee

  • REC reference

    21/SW/0006

  • Date of REC Opinion

    11 Feb 2021

  • REC opinion

    Further Information Favourable Opinion