Profiling latent CMV infection in Early Inflammatory Arthritis

• Research type

  Research Study

• Full title

  Assessing CMV-specific immunity in the Early Arthritis patient cohort in Brighton.

• IRAS ID

  270953

• Contact name

  Florian Kern

• Contact email

  F.Kern@bsms.ac.uk

• Sponsor organisation

  University of Sussex

• Duration of Study in the UK

  2 years, 1 months, 3 days

• Research summary

  Cytomegalovirus (CMV) is thought to have a great impact on the immune system in terms of its cellular composition. CMV does not causes symptoms healthy people. In Early Arthritis the immune system becomes overactive and attacks the joints, causing arthritis. CMV-infected patients with arthritis have more severe disease. No systematic study has been completed to see what the additional effects of CMV infection are on the immune system of patients with Early Arthritis. We will take blood samples and analyse them in order to identify possible changes in the immune cells relating to CMV infection. This information could be used to separate patients with respect to course of disease (significant or minimal disability).

• REC name

  Yorkshire & The Humber - Leeds West Research Ethics Committee

• REC reference

  22/YH/0060

• Date of REC Opinion

  22 Feb 2022

• REC opinion

  Favourable Opinion