Priming Exercise in Type 1 Diabetes
Research type
Research Study
Full title
The Effects of Prior Exercise on Pulmonary Oxygen Uptake Kinetics and the Power-Duration Relationship in Type 1 Diabetes
IRAS ID
222429
Contact name
Richie Philip Goulding
Contact email
Sponsor organisation
Liverpool Hope University
Duration of Study in the UK
0 years, 7 months, 1 days
Research summary
Critical power is an important threshold in exercise physiology, and is an important determinant of the ability to tolerate high-intensity exercise. The ability to tolerate such exercise is drastically impaired in certain chronic conditions, such as type 1 diabetes. Whilst the most important physiological factors that determine critical power have yet to be determined, previous work from our laboratory suggests that it is related to the speed of oxygen uptake at the onset of exercise. This study will look to utilise “priming” exercise as an intervention to improve the speed of these oxygen uptake “kinetics”, and thus critical power and exercise tolerance in individuals with type 1 diabetes.
Individuals with type 1 diabetes between the ages of 18-40 years without any significant complications and with a disease duration of 2-20 years will be eligible for the study.
The study will be conducted in the Sports Performance laboratories at Liverpool Hope University. The study will last for 3-9 weeks for each participant, and will involve 9 separate visits to the laboratory. The first visit will assess the maximum exercise capacity of each participant. This visit will involve a maximal exercise test to determine the maximum amount of oxygen each participant can utilise during high-intensity exercise. The subsequent visits will involve exhaustive exercise tests conducted at fixed intensities. A total of four separate intensities will be used; on four occasions these will be preceded by no prior exercise, and on four other occasions these will be preceded by a prior bout of priming exercise. All tests will be performed on a type of stationary bicycle known as an ergometer. These tests will inform us whether priming exercise can be utilised as an intervention to improve critical power (and thus exercise tolerance) in type 1 diabetes.REC name
East Midlands - Derby Research Ethics Committee
REC reference
17/EM/0352
Date of REC Opinion
6 Oct 2017
REC opinion
Further Information Favourable Opinion