PRIM-SDR

• Research type

  Research Study

• Full title

  PRIM-SDR: Predicitive Role of Intraoperative Monitoring in Selective Dorsal Rhizotomy

• IRAS ID

  292820

• Contact name

  John R Goodden

• Contact email

  j.goodden@nhs.net

• Sponsor organisation

  Studienzentrale, Studienzentrum Bonn

• Duration of Study in the UK

  2 years, 9 months, 29 days

• Research summary

  The impact of the relationship between clinical extent of spasticity and the intra-operatively deter-mined responses of the myotomes in the EMG measurement are unknown. However, intraoperative use of EMG measurements is the standard operating procedure in selective dorsal rhizotomy which aids decision-making of which rootlets undergo resection. It is not ethical to refuse children a selective dorsal rhizotomy without intraoperative EMG measurements because EMG is a standard intra-operative tool useful for anatomical orientation and safety. Therefore, the scope of this study is to analyse the predictive role of intra-operative EMG monitoring by investigating the relationship between clinical extent of spasticity and the intraoperative EMG responses in defined myotomes.

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  21/YH/0118

• Date of REC Opinion

  16 Aug 2021

• REC opinion

  Further Information Favourable Opinion