Prevention and management of serious events in HIV positive patients
Research type
Research Study
Full title
Use of a retrospective methodology to examine the process of care surrounding serious non-HIV related events in HIV positive patients: a feasibility study.
IRAS ID
164956
Contact name
Martin Fisher
Contact email
Sponsor organisation
BSUH
Duration of Study in the UK
0 years, 5 months, 5 days
Research summary
This pilot study will determine the feasibility of research planned for a future NIHR Programme Development Grant in which we intend to develop and evaluate a new model of care to better meet the needs of an ageing population of people living with HIV.
We will examine the feasibility of a retrospective methodology based on the National Confidential Enquiry of Patient Outcomes and Death (NCE-POD) to 1) examine the process of care of HIV positive patients who have serious medical events (myocardial infarction, stroke, drug-drug interaction, chronic kidney disease stage 3), 2) identify aspects of care that could have been provided differently in order to enhance the care of HIV positive patients and 3) use these insights to make recommendations for the future delivery of care.
The study will run across three HIV clinics. HIV positive patients aged =16 years who have experienced one of the events within the previous 3 years will be identified by a member of the local clinical team (total n=36). For this pilot study, purposive sampling will be used to select patients with illustrative cases from the list generated. Patients will be identified and contacted by their HIV clinical team and informed consent will be sought for the research team to access medical notes and obtain information via questionnaires from clinicians involved in their care from up to 18 months before the episode, to 12 months after.
Patients will not be required to complete any questionnaires or undertake any study procedures/interventions. Anonymised questionnaires and casenotes will be reviewed by an independent panel of HIV and secondary care specialists, general practitioners, HIV pharmacist and HIV specialist nurses to assess the quality of care and identify ways in which care could have been improved. The primary outcome of this pilot study will be the feasibility of this approach as determined by the proportion of patients approached who provide written informed consent, proportion questionnaires returned by clinicians and quality of data.REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
15/WM/0039
Date of REC Opinion
30 Jan 2015
REC opinion
Favourable Opinion