Prevalence of DIP
Research type
Research Study
Full title
Prevalence and prediction of drug-induced photosensitivity
IRAS ID
244549
Contact name
Lesley Rhodes
Contact email
Sponsor organisation
University of Manchester
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 5 months, 31 days
Research summary
DIP is the reaction between sunlight and a specific chemical agent, leading to adverse cutaneous reactions. Although natural sunlight is involved mostly in DIP, artificial light can also cause significant reactions. The DIP mechanisms, broadly attributable to phototoxicity and photoallergy, occur when UVR, particularly UVA and sometimes UVB, wavelengths are absorbed by photosensitising agents such as systemic drugs or topically applied chemicals. Identification of the present-day drugs most often associated with photosensitivity, and of the people most affected, could help doctors avoid giving culprit drugs to susceptible patients.
In this study, a one-page anonymous questionnaire which contains nine questions will be used to ask participants about their current medication and the effect of sun exposure on their skin. The questionnaire will be used to collect the information from individuals who are attending the accident and emergency (A&E) department at Salford Royal Hospital. The overall aim of this study is to explore how common DIP is in the community and to define characteristics making some people susceptible to drug reactions. The study will provide important information on the prevalence and effects of DIP in the community.REC name
West of Scotland REC 4
REC reference
18/WS/0130
Date of REC Opinion
3 Aug 2018
REC opinion
Further Information Favourable Opinion