Prevalence of depression and anxiety post-myocardial infarction
Research type
Research Study
Full title
Post Myocardial Infarction Anxiety and Depression (p-MIAD) rates pilot study
IRAS ID
188609
Contact name
Richard Holt
Contact email
Duration of Study in the UK
0 years, 4 months, 7 days
Research summary
Cardiovascular disease (CVD), which includes coronary heart disease, stroke and peripheral vascular disease, is the leading cause of mortality worldwide. Cardiovascular morbidity remains a substantial clinical and economic burden as more people survive with CVD. In over 90% of cases, the risk of a first myocardial infarction is related to the nine modifiable risk factors: dyslipidaemia, hypertension, obesity, poor diet, physical inactivity, diabetes, smoking, excess alcohol consumption and psychosocial stress. Of these, 5-10% of CVD is attributed to smoking. Effective management of these risk factors could significant reduce the burden of cardiovascular disease. Mental illness is also common, affecting approximately 1 in 10 people at any one time. The World Health Organisation predicts that by 2030, depression alone will be the second leading cause of disability worldwide after CVD. Depression is associated with increased all-cause mortality across a broad range of physical diseases as well as traumatic deaths and suicide. Cardiovascular disease is the commonest cause of death and is increased 1.5-2.0 fold in both men and women with depression, independent of other risk factors. Similarly CVD is increased with people with anxiety disorders, with anxiety appearing to be an independent risk factor for incident coronary heart disease and cardiac mortality. Given the high prevalence of both CVD and depression and anxiety, a degree of co-morbidity is to be expected but it is clear that depression occurs more commonly among people with CVD than expected, and vice versa.
In this study we aim to investigate the prevalence of mood disorders (anxiety and depression) in patients who present with first myocardial infarction at the Southampton General Hospital.REC name
South Central - Hampshire B Research Ethics Committee
REC reference
15/SC/0573
Date of REC Opinion
24 Nov 2015
REC opinion
Further Information Favourable Opinion