Predictors of pacemakers after implanting an artificial valve V1.0
Research type
Research Study
Full title
Predictors of requiring a permanent pacemaker implantation following transcatheter aortic valve implantation in the West of Scotland
IRAS ID
338892
Contact name
Daniel Newman
Contact email
Sponsor organisation
NHS Golden Jubilee University National Hospital
Duration of Study in the UK
0 years, 8 months, 31 days
Research summary
The aortic valve separates the left ventricle and the aorta. Blood flow out of the heart is restricted when this valve is diseased. It can be treated by surgical replacement or by inserting a new valve, called a Transcatheter Aortic Valve Implantation (TAVI), through an artery in the leg up to the heart which then takes over from the diseased valve. TAVI was developed for patients who are unsuitable for surgery. A potential side effect of the TAVI procedure is that the heartrate becomes very slow. It can recover over time but if it doesn’t, a pacemaker can be implanted into the patient to increase the heartrate.
In this study, we aim to determine the number of patients who received a pacemaker within 30 days after their TAVI procedure and whether there is a pattern linking patients who had a TAVI and a pacemaker. To achieve this, information from previous TAVI procedures performed at the Golden Jubilee Hospital in Scotland between 2018 and 2024 will be collected and analysed. There will be two groups of patients: those who received a pacemaker within 30 days after TAVI and those who did not receive a pacemaker within 30 days after TAVI.This work will help us understand whether you can predict how likely it is that a patient will need a pacemaker following their TAVI procedure. If a patient has a high risk of needing a pacemaker after the TAVI procedure, then the appropriate steps can be taken to ensure the clinical team are prepared for that outcome. The risk of needing a pacemaker can be discussed with patients before the TAVI procedure ensuring they are fulling informed before consenting. High-risk patients can also receive close monitoring following the TAVI procedure.
REC name
East Midlands - Nottingham 1 Research Ethics Committee
REC reference
24/EM/0196
Date of REC Opinion
9 Sep 2024
REC opinion
Favourable Opinion