Predictive Model of Mortality and Major Morbidity in Neonates
Research type
Research Study
Full title
Predictive Model of Mortality and Major Morbidity in Neonates in the Perinatal Period
IRAS ID
287049
Contact name
Mallinath Chakraborty
Contact email
Sponsor organisation
Cardiff and Vale University Health Board
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Worldwide, preterm babies are at increased risk of death or major complications after birth. The earlier in gestation a baby is born, the higher is thier risk of the above complications. Parents and healthcare workers are routinely faced with difficult conversations and decisions when there is the prospect of a premature birth. An ability to provide predictions of outcome would benefit these discussions and identify at-risk infants more accurately.
Using detailed clinical information around the time of birth from Welsh mothers and babies, we propose to derive mathematical models for the prediction of neonatal mortality and major-morbidity. We intend to use both linear as well as complex machine-learning models and test their validity against external data from Welsh babies and finally from a large cohort of English babies. The model will be presented as an online implementation for visualisation purposes only.REC name
London - Brent Research Ethics Committee
REC reference
22/PR/0147
Date of REC Opinion
16 Feb 2022
REC opinion
Favourable Opinion