Prediction of Gestational Diabetes In Obese Women: a validation study
Research type
Research Study
Full title
Prediction of Gestational Diabetes in Obese Pregnant Women: a validation study.
IRAS ID
224961
Contact name
Lucilla Poston
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
1 years, 6 months, 30 days
Research summary
Obesity is increasing worldwide. In pregnancy obesity is associated with an increased risk of developing gestational diabetes (GDM), a disorder which can make babies grow too big in the womb, causing difficulties in labour amongst many other complications for mother and child. A recent trial in obese pregnant women (UK Pregnancies Better Eating and Activity Trial: UPBEAT) enabled us to develop an early pregnancy test for identification of obese women at greatest risk of getting GDM. This is a simple test which involves the measurement of blood pressure, maternal size (circumferences and skin folds), age and biomarkers in the blood. This test would be undertaken during a routine antenatal visit when clinical blood samples are taken. We want to use this test to better identify obese women at greatest risk of GDM so that we can treat them early in pregnancy and prevent GDM. However before we can do this we need to make sure the test works in a new non-trial population of obese pregnant women. This is the aim of this current project.
REC name
South West - Frenchay Research Ethics Committee
REC reference
18/SW/0212
Date of REC Opinion
17 Sep 2018
REC opinion
Favourable Opinion