Predicting Infant Extubation Success Using Surface EMG During SBT.
Research type
Research Study
Full title
Predicting Infant Extubation Success Using Surface Electromyography During Spontaneous Breathing Test
IRAS ID
274361
Contact name
Anne Greenough
Contact email
Sponsor organisation
King’s College London
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Many babies admitted to the neonatal unit require help via a breathing machine (ventilator). Support from a ventilator can be life-saving, but remaining on a ventilator for a long time can increase the risk of complications. However, if a baby is taken off a ventilator too early then they can struggle to cope with breathing for themselves, and need to go back onto the ventilator. This means they would also need to have a breathing tube put back into the windpipe. It can be difficult to predict when a baby is ready to be taken off the ventilator, 20-30% of babies fail having the breathing tube being removed (extubation), and we are therefore trying to find new ways to be able to tell if a baby is ready, to optimize care.\n\nCurrent methods are yet to outperform clinical judgement in predicting those infants at risk of failed extubation. Therefore, we propose combing two methods to see if we can increase the accuracy of predicting successful extubation. The two methods are: \n(1)\tMeasuring the electrical activity of the diaphragm (the main muscle of breathing), which is non-invasive and done through attaching three small stickers to your baby’s chest, \n(2)\tA spontaneous breathing test, (which is where a baby’s ventilation settings are reduced for ten minutes to assess the baby with less support from the machine). \nBoth methods have been shown to be useful but not 100% accurate individually and combining the two may be more useful and beneficial. \n\nOur aim is to determine whether during a spontaneous breathing test, measuring the electrical activity of the diaphragm will add further diagnostic accuracy to if a baby can be successfully extubated. \t\n
REC name
South West - Central Bristol Research Ethics Committee
REC reference
20/SW/0062
Date of REC Opinion
29 May 2020
REC opinion
Further Information Favourable Opinion