PREDICT VF II
Research type
Research Study
Full title
Prospective Evaluation Of Exercise-Induced Cardiac Conduction Instability In Predicting Ventricular Fibrillation Events In Hypertrophic Cardiomyopathy (PREDICT-VF 2)
IRAS ID
225117
Contact name
Prapa Kanagaratnam
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
5 years, 1 months, 1 days
Research summary
Hypertrophic Cardiomyopathy (HCM) is an inherited heart condition. Most people who have it are unaware of any problems relating to it. Unfortunately, a small number of people with the condition can suddenly develop a dangerous fast heart beat that can lead to death. There is no cure, but implanting a cardioverter-defibrillator (ICD), which is like a pacemaker can save the life of affected individuals. However, ICD implantation has its own problems, so choosing who gets an ICD is a very important decision.
The current approach for recommending people for an ICD has limitations and a better method is needed. We have developed a new technique called the 'Ventricular Conduction Stability' (V-CoS). This involves wearing a special vest which records electrical signals from the heart, and then running on a treadmill. We have used it to identify abnormalities in the hearts of people with (HCM) who have also survived a life-threatening event.
This project aims to test our new tool against current methods to ascertain which is better at identifying patients who should have an ICD.
REC name
London - Fulham Research Ethics Committee
REC reference
18/LO/0049
Date of REC Opinion
8 Mar 2018
REC opinion
Further Information Favourable Opinion