PREDICT: Thinking about Pregnancy Risk in Women with Kidney Disease

• Research type

  Research Study

• Full title

  PREDICT: Thinking about Pregnancy Risk in Women with Kidney Disease

• IRAS ID

  274525

• Contact name

  Kate Bramham

• Contact email

  kate.bramham@kcl.ac.uk

• Sponsor organisation

  King's College London

• Duration of Study in the UK

  0 years, 10 months, 17 days

• Research summary

  Currently, there is no robust evidence about how women with Chronic Kidney Disease (CKD) perceive pregnancy risk. The aim of this research is to improve understanding of women with CKD’s perception of risk in pregnancy.
  In order to provide appropriate pre-pregnancy and antenatal counselling including accurate presentation of risk of pregnancy outcomes, it is important to establish how do women with CKD perceive their pregnancy risk. In addition, to facilitate discussion about pregnancy for women with CKD, it is critical to understand key biopsychosocial factors influencing their risk perceptions.

  This study will be conducted in two phases. In phase one, risk perceptions in women with CKD who are contemplating pregnancy will be quantitatively measured and potential influencing biopsychosocial factors assessed including their illness perceptions, quality of life, anxiety, depression and perceived social support. Demographic, medical and pregnancy histories will also be collected. Phase one findings will establish how do women with CKD perceive their risk and the biopsychosocial factors associated with risk perception will be established.

  In phase two, perception of risk and intentions will be qualitatively explored in women with CKD who perceive high and low degrees of risk. This sub-study will facilitate understanding about which factors and experiences impact risk perception and their relationship with pregnancy intentions.

  This study will establish whether there is a greater need for risk communication for women with CKD to develop accurate risk perceptions and will insight into key factors which drive risk perceptions which will facilitate effective future risk communication. The findings of this research will inform how a clinical predictive tool is delivered to CKD women (PREDICT – Pregnancy-associated progression of chronic kidney Disease: development of a Clinical predictive Tool).

• REC name

  London - Bloomsbury Research Ethics Committee

• REC reference

  20/LO/0257

• Date of REC Opinion

  18 May 2020

• REC opinion

  Further Information Favourable Opinion