PRE18FFIR-TIME
Research type
Research Study
Full title
Prediction of Recurrent Events with 18F-Fluoride to Identify Ruptured and High-risk Coronary Artery Plaques with Myocardial Infarction - The Investigation of Temporal Change
IRAS ID
173188
Contact name
Laura Forsyth
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
3 years, 7 months, 3 days
Research summary
Heart attacks are most commonly caused by inflammation or rupture of fatty deposits (plaques) within the wall of heart blood vessels. It appears that this process can also frequently occur without causing any symptoms but may put patients at increased risk of heart attacks in the future. It has also been shown that patients with a heart attack often have more than one plaque that has recently ruptured. Previous research has shown a specialised scanner known as a PET (positron emission tomography) scan can identify these inflamed or ruptured plaques in patients with a recent heart attack. We intend to see if the presence of these plaques can be used to predict recurrent heart attacks. This study will involve patients undergoing two PET scans over the course of a year to define the dynamic changes in plaque vulnerability following a heart attack.
REC name
South East Scotland REC 01
REC reference
16/SS/0025
Date of REC Opinion
17 Mar 2016
REC opinion
Further Information Favourable Opinion