PRE18FFIR-IMAGE
Research type
Research Study
Full title
Prediction of Recurrent Events with 18F-Fluoride to Identify Ruptured and High-risk Coronary Artery Plaques with Myocardial Infarction - In Vivo Multimodal Intracoronary Imaging to Enable Plaque Characterisation
IRAS ID
173206
Contact name
Laura Forsyth
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
3 years, 3 months, 3 days
Research summary
Heart attacks are caused by a blood clot which stops blood flowing to part of the heart muscle. The blood clots form in areas of blood vessels (arteries) that are damaged (inflamed) by a build up of small fatty lumps (plaques). The fatty lumps can break and cause blood to stick to the wall of the blood vessel. It appears that this process can also occur without causing any symptoms and may put patients at increased risk of heart attacks in the future. It has also been shown that patients with a heart attack often have more than one damaged plaque. Previous research has shown a specialised scanner known as a PET (positron emission tomography) scan can identify these damaged plaques in patients with a recent heart attack. We intend to see if the presence of these plaques can be used to predict heart attacks in the future. This study will involve patients undergoing intracoronary imaging to help understand the plaque characteristics that affect tracer uptake.
REC name
South East Scotland REC 01
REC reference
16/SS/0021
Date of REC Opinion
17 Mar 2016
REC opinion
Further Information Favourable Opinion