Posterior Fossa ICH – data pooling project
Research type
Research Study
Full title
Does surgery reduce mortality in patients with a cerebellar ICH? Observations from an international, multicentre, pooled data set.
IRAS ID
220618
Contact name
Adrian Parry-Jones
Contact email
Sponsor organisation
University of Manchester
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
This project will assess whether surgery after a bleed in the back of the brain (posterior fossa) reduces the risk of death.
1 in 5 strokes are caused by intracerebral haemorrhage (ICH), a bleed into brain tissue. ICH in the back of the brain; brain stem or cerebellum and known as the posterior fossa, is rare but carries the highest risk of death (mortality). Current treatment options are limited and it is unclear which patients would benefit from surgery. The current literature is also limited, as individual research groups see too few patients for results to be generalizable.The aim of this study is to pool anonymised data from existing clinical registries of ICH patients which held at neurosurgical and stroke centres in the UK, in order to look at the factors involved in clinical decision making and establish whether surgery does improve outcome for patients with this condition.
A medical student, working under the supervision of a senior researcher at Salford Royal Hospital will compare the death rates at 30days in patients who had surgery with those who did not, look at the type and timing of surgery and assess its impact on 30d mortality. The analysis is expected to take approximately 6 months.
REC name
London - Dulwich Research Ethics Committee
REC reference
17/LO/0315
Date of REC Opinion
20 Feb 2017
REC opinion
Favourable Opinion