Post-mortem dual-energy CT

  • Research type

    Research Study

  • Full title

    Post-mortem dual energy computed tomography (SORT)

  • IRAS ID

    208079

  • Contact name

    Fergus Gleeson

  • Contact email

    fergus.gleeson@ouh.nhs.uk

  • Sponsor organisation

    Joint Research Office

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    This is a study looking at the use of a special CT, namely dual-energy computed tomography (DECT), for finding and studying clots in the heart and lungs. Autopsy has been the traditional method for determining the cause of death when it is not unknown. However, due to its destructive nature, autopsy is not always preferred and less invasive options such as CT are being increasingly looked at and used in clinical practice.

    Recent developments in imaging technology allow us to find the makeup of body tissues, such as the proportion of fat or fibre in a muscle. This study takes advantage of this development, and aims to show the difference between blood clots that have formed before and after death. Because blood clots in the heart and lungs are a major cause of death in our elderly patients and that blood normally clots after it stops flowing in the event of death itself, it is important that we have a way to tell the difference between the two, so we get to know whether a clot that we see on CT might have been the cause of death.

  • REC name

    South Central - Oxford B Research Ethics Committee

  • REC reference

    17/SC/0654

  • Date of REC Opinion

    22 Dec 2017

  • REC opinion

    Unfavourable Opinion