POSE-trial
Research type
Research Study
Full title
PERI-INTERVENTIONAL OUTCOME STUDY IN THE ELDERLY (POSE): EUROPEAN, MULTI-CENTRE, PROSPECTIVE OBSERVATIONAL COHORT STUDY
IRAS ID
231925
Contact name
Tamas Szakmany
Contact email
Sponsor organisation
Aneurin Bevan University Health Board
Duration of Study in the UK
1 years, 1 months, 31 days
Research summary
In Europe, it is estimated that the elderly population (≥80 years) will increase from 5.3% of
the total population in 2015 to 9% in 2040. Little is known about the peri-interventional 30-day mortality rates in the elderly population. Compared with younger patients, the elderly are at greater risk of mortality and morbidity after elective and especially emergency surgery. POSE aims to be the first study to create evidence on peri-interventional mortality and outcome in the elderly population undergoing surgery / non-surgical intervention where an anaesthetist was present. Comparative effectiveness research using a “real life” observational study design is an appropriate and effective approach with favourable external validity. The POSE study will include a large sample of all surgical and non-surgical interventional patients ≥80 years across Europe. It will determine the peri-interventional (surgical and non-surgical interventional) all-cause mortality rate on day 30.REC name
Wales REC 1
REC reference
17/WA/0305
Date of REC Opinion
5 Oct 2017
REC opinion
Unfavourable Opinion