POP KD. Version 1.0

  • Research type

    Research Study

  • Full title

    Perspectives of Pregnancy Experience in women with Kidney Disease

  • IRAS ID

    219115

  • Contact name

    Kate Bramham

  • Contact email

    kate.bramham@nhs.net

  • Sponsor organisation

    King’s College Hospital NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 3 months, 22 days

  • Research summary

    Kidney disease affects 3% of women of childbearing age. Women with chronic kidney disease (CKD) are at higher risk of complications in pregnancy including high blood pressure, pre-eclampsia, worsening kidney function, miscarriage, stillbirth, preterm delivery and small for gestational age infants. Recent studies suggest that even those with CKD stage 1 (normal kidney function but abnormal structure or urinalysis) have a higher rate of adverse pregnancy outcomes compared with healthy controls. Despite this most women with kidney disease have successful pregnancies and healthy babies.
    National Institute of Clinical and Health Excellence (NICE) guidelines recommend that women with chronic medical conditions, including CKD, should receive counselling prior to pregnancy in order to optimise health and medication use, plan timing of pregnancy and to inform women about possible maternal and fetal outcomes, which is supported by the recent UK maternal deaths confidential enquiry (MBRRACE 2016). Women with chronic medical conditions are also advised to receive heightened surveillance during antenatal and peripartum care according to NICE Pre-Conception - Advice and Management(2012). Therefore when women with kidney disease are pregnant they receive care from a team of different specialists including kidney doctors (nephrologists), obstetricians and midwives. There are few qualitative assessments of women with CKD’s attitudes of pregnancy. We would therefore like to know more about women’s experience of planning a pregnancy and the care received during and after their pregnancies.
    We believe this information will help us improve the experience of pregnancy for women with kidney disease and eventually the findings of this study will inform provision of specialist pre-pregnancy, antenatal and postpartum care for women with CKD, to enable development of a patient focused service.

  • REC name

    London - Stanmore Research Ethics Committee

  • REC reference

    17/LO/0759

  • Date of REC Opinion

    31 May 2017

  • REC opinion

    Further Information Favourable Opinion