POP-ECG-HF-AF

  • Research type

    Research Study

  • Full title

    A Prospective Observational Study of Prolonged Electrocardiographic Monitoring in Patients with Heart Failure in Sinus Rhythm or Atrial Fibrillation

  • IRAS ID

    187491

  • Contact name

    Yura Mareev

  • Contact email

    Y.Mareev@rbht.nhs.uk

  • Sponsor organisation

    Imperial College London and Imperial College Healthcare NHS Trust

  • Duration of Study in the UK

    5 years, 0 months, 1 days

  • Research summary

    Patients with heart failure may experience a variety of irregular heart rhythms (arrhythmia) that may or may not be symptomatic. There is a surprising lack of information on arrhythmias in contemporary populations of patients with heart failure, particularly on brady-arrhythmias. New, wearable technologies enable monitoring for much longer periods of time.

    We intend to conduct an observational study in patients with heart failure, investigating the incidence of arrhythmias using a wearable device that can monitor heart rhythm for up to 14 days. In addition to gathering routine clinical information, research assessments include a symptoms questionnaire and a corridor walk test. Patients will be followed for clinical events (interventions for arrhythmias, hospitalisation, death) for up to 5 years.

    If we discover serious arrhythmias, these will be treated according to expert guidelines. We also pre-specify a broader group of arrhythmias that might indicate a worse prognosis and become targets for therapy in the future.

  • REC name

    London - Brent Research Ethics Committee

  • REC reference

    15/LO/1779

  • Date of REC Opinion

    5 Nov 2015

  • REC opinion

    Favourable Opinion