Point of care biopsy device for breast cancer
Research type
Research Study
Full title
Analysis of breast tissue samples in the development of a point of care biopsy device for the diagnosis of breast cancer
IRAS ID
294430
Contact name
R Steven Conlan
Contact email
Sponsor organisation
Swansea University
Duration of Study in the UK
0 years, 10 months, 31 days
Research summary
Research Summary
This study will explore the feasibility of using ambient mass spectroscopy ionisation to differentiate benign and malignant breast tissues. This proof of concept work will lay the foundation for a novel point of care breast cancer diagnostic tool.
Summary of Results
This research aimed to help create a new tool for studying tissues and detecting breast cancer. The tool would analyse tiny samples of tissue and fluid from the body. The study found important information, including:
Finding specific fat markers that can tell the difference between healthy and breast cancer tissue.
Developing a way to measure the amount of the cancer marker fats using a special method.
Figuring out the best conditions to prepare the tissue samples so the fats can be studied. This involved testing different ways to prepare the samples.
Confirming that the chosen fats are good marker indicators to tell if tissue is healthy or has breast cancer.
Figuring out how sensitive the tool needs to be to detect these changes in fats.
In simple terms, the study discovered how to use fats to identify breast cancer and how to make a new tool to do this.REC name
West Midlands - Edgbaston Research Ethics Committee
REC reference
21/WM/0061
Date of REC Opinion
19 May 2021
REC opinion
Further Information Favourable Opinion