Plasma sodium concentration and the risk of cardiovascular disease
Research type
Research Study
Full title
Plasma sodium concentration and the risk of cardiovascular disease: a large community-based cohort study
IRAS ID
190429
Contact name
Nicholas I Cole
Contact email
Sponsor organisation
Epsom and St Helier University Hospitals NHS Trust
Duration of Study in the UK
0 years, 4 months, 4 days
Research summary
Reducing the amount of salt in our diet helps to lower blood pressure as well as the risk of cardiovascular disease, including heart disease and stroke. Why this is the case is not fully understood, but there is evidence that the concentration of sodium in our blood might be important. Previous studies have shown that eating more salt can lead to small increases in the blood sodium concentration, and that this can increase blood pressure and affect the function of blood vessels. These effects might increase the risk of cardiovascular disease but this has not been investigated before. Therefore, this study aims to be the first to find out whether people with higher blood sodium concentration have a higher risk of developing cardiovascular disease. It will do this by examining the electronic health records of patients from GP practices around the United Kingdom.
REC name
London - Stanmore Research Ethics Committee
REC reference
15/LO/1865
Date of REC Opinion
19 Oct 2015
REC opinion
Favourable Opinion