Plasma Ammonia Stability Study (PASS)

  • Research type

    Research Study

  • Full title

    Plasma Ammonia Stability Study

  • IRAS ID

    182980

  • Contact name

    Lesley Tetlow

  • Contact email

    Lesley.Tetlow@cmft.nhs.uk

  • Sponsor organisation

    Central Manchester University Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Measuring ammonia in blood is an important part of the medical treatment and monitoring of children with certain inherited metabolic conditions, or patients who are very sick and have low levels of consciousness. The accuracy of the test can be affected by variety of factors that are not related to illness such as delay in getting the sample to the laboratory or when the red blood cells in the sample break apart outside the body. The purpose of our study is to evaluate the effects of these sorts of blood sample quality issues on the level of ammonia we measure in the blood.

  • REC name

    North West - Greater Manchester Central Research Ethics Committee

  • REC reference

    16/NW/0045

  • Date of REC Opinion

    14 Mar 2016

  • REC opinion

    Further Information Favourable Opinion