Pilot study to investigate repair of early erosion
Research type
Research Study
Full title
Pilot study to investigate the reparative effect of Regenerate® on enamel against a dietary acid exposure utilising an impression technique to capture in vivo images of teeth
IRAS ID
182014
Contact name
Nicola West
Contact email
Sponsor organisation
Unilever
Duration of Study in the UK
0 years, 3 months, 4 days
Research summary
The study design is a randomised, split mouth, blind with respect to study analysts (microscopist, image grader) two treatment clinical study in 10 healthy participants with sound tooth enamel. The study will comprise of a screening visit, pre-baseline visit and 5 subsequent clinic visits. At the screening visit, participants will give consent to participate in the study. Medical history and concomitant medications will be recorded. Eligibility will be determined following an oral soft tissue (OST) examination and an evaluation of dentition exclusions. Two suitable anterior teeth will be identified for study assessments, these teeth must be at least one tooth apart in the mouth. Saliva samples will be collected from the participants at set points during the study to look at any changes in salivary pH.
REC name
South West - Central Bristol Research Ethics Committee
REC reference
15/SW/0141
Date of REC Opinion
11 Jun 2015
REC opinion
Favourable Opinion