PIIPeR Trial: Feasibility Study

• Research type

  Research Study

• Full title

  PIIPeR Trial: Impact of Paediatric Intensive Interdisciplinary Pain Rehabilitation for children with chronic pain and pain-related disability. Feasibility of recruitment to a randomised trial.

• IRAS ID

  343593

• Contact name

  Suellen Walker

• Contact email

  Suellen.Walker@gosh.nhs.uk

• Sponsor organisation

  Great Ormond Street Hospital NHS Foundation Trust

• ISRCTN Number

  ISRCTN00045807

• Clinicaltrials.gov Identifier

  ISRCTN Provisional Reference Number, 45807

• Duration of Study in the UK

  2 years, 0 months, days

• Research summary

  One in twenty teenagers experience chronic pain that lasts many months and affects their activities, mood, sleep and ability to go to school. These young people often need extra healthcare, and many are referred to pain clinics. 

  At Great Ormond Street Hospital (GOSH) Chronic Pain Clinic, a specialist team (doctors, nurses, physiotherapists, psychologists) see children and their families. A plan is made to help manage the pain, with treatment and follow-up at separate outpatient appointments.

  An intensive pain rehabilitation programme (PPRP) that combines all treatments at the same time can be more effective for some young people. An interdisciplinary team work together to deliver group and individual sessions for young people and parent/carers each day over several weeks.

  We are now doing research to test PPRP as a treatment option within the GOSH Pain Service. We will invite eligible young people (11-18 years) to join the Paediatric Intensive Interdisciplinary Rehabilitation (PIIPeR) Trial. We need to know more about:
  • how effective PPRP is
  • whether the timing of PPRP makes a difference
  • which parts work best
  • which children are helped the most

  Patients and families who agree will be randomly allocated to either PPRP-Early (start within 1-3 months) or continue usual Pain Clinic care until PPRP-Delayed (start within 6-9 months). The young person and a parent/carer will attend Monday to Friday for 3 weeks of care that includes: pain education; joint psychology, physiotherapy, and occupational therapy sessions; parental support and skills training.

  We will ask young people and parents:
  • if the different timings are acceptable
  • to fill in questionnaires about how pain affects their activities, schooling, mood and thoughts, and health care needs
  
  We will repeat questionnaires 3 and 6 months later to check how participants and families are doing.

  The study will be at GOSH, with funding via GOSH Charity.

• REC name

  London - Central Research Ethics Committee

• REC reference

  24/LO/0680

• Date of REC Opinion

  30 Sep 2024

• REC opinion

  Further Information Favourable Opinion