PIGMI
Research type
Research Study
Full title
Post-operative Imaging in high grade Glioma: is Management Influenced? (PIGMI study)
IRAS ID
283827
Contact name
Thomas Booth
Contact email
Sponsor organisation
King’s College London
Clinicaltrials.gov Identifier
n/a, n/a
Duration of Study in the UK
0 years, 6 months, 12 days
Research summary
Research Summary:
Magnetic resonance imaging (MRI) likely plays an important role in the management of high grade glioma. Appropriate and timely neuroimaging in the follow up period is believed to be crucial in making subsequent management decisions. However, there is a paucity of literature providing evidence to support that idea.
The aim of this study is to determine whether neuroimaging performed at each component of the patient pathway after initial high grade glioma treatment, actually results in a real change in management (as opposed to a perceived change in management). The main emphasis is on all imaging used at the time of a multidisciplinary team meeting (MDMT), however, we will also study specifically dynamic susceptibility contrast-enhanced (DSC) MRI and dynamic contrast enhanced (DCE) MRI.
We will perform this through the format of a MDM to be compatible with real life decisions. Using the retrospective identical information available at the MDM i.e. compiled recent correspondence, histopathological and molecular information the MDM members (oncology nurse, oncologist, neurosurgeon, neuroradiologist, pathologist/molecular scientist) will prospectively determine the patient management with and without the imaging.
Summary of results: No recruits per se (mock MDTM) Study completed at 2 sites Data being analysed Results will be published.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
20/YH/0283
Date of REC Opinion
29 Sep 2020
REC opinion
Further Information Favourable Opinion