PICASSO v1.0

  • Research type

    Research Study

  • Full title

    PICASSO Prostate Investigation: Cambridge Approach for cancer Screening, Stratification and treatment Options

  • IRAS ID

    355186

  • Contact name

    Harveer Dev

  • Contact email

    hsd26@cam.ac.uk

  • Sponsor organisation

    Cambridge University Hospitals NHS Foundation Trust and University of Cambridge

  • Duration of Study in the UK

    10 years, 0 months, 1 days

  • Research summary

    Why?
    PICASSO is an exploratory translational study in prostate cancer, aiming to:

    - Improve diagnosis and relapse detection.
    - Identify patients who may benefit from additional treatments before/after surgery.
    - Discover biomarkers to guide treatment and improve outcomes.

    This research addresses critical gaps in prostate cancer care, with the overall goal of improving patients outcomes by informing more precise diagnostics and treatments.

    What?
    The study focuses on prostate cancer and investigates biomarkers, pharmacotherapies, and treatment strategies.

    Who?
    Men aged 16+ at any stage of their prostate cancer journey or that do not have prostate cancer but are considered adequate control cases.

    Where?
    Cambridge University Hospitals NHS Foundation Trust (CUHFT).

    How?
    PICASSO collects and analyses various samples (blood, urine, tissue, semen), imaging data, and clinical information. These are examined using standard and advanced technologies in Cambridge and through collaborators.

    The study runs alongside standard clinical care or other research studies, allowing real-time translational research at key points in a patient’s cancer journey. Retrospective data and samples will also be utilized to enable long-term follow-up and further research.

  • REC name

    West of Scotland REC 5

  • REC reference

    25/WS/0071

  • Date of REC Opinion

    28 May 2025

  • REC opinion

    Unfavourable Opinion