Physiologic Pacing Registry
Research type
Research Study
Full title
Physiologic Pacing Registry
IRAS ID
281799
Contact name
Rebecca Malpass
Contact email
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 6 months, 22 days
Research summary
Electrical conduction allows for the heart to pump and maintain the pace required for a person to function normally. Patients with cardiac disease and heart failure associated to abnormal electrical conduction of the heart may benefit from a therapy that resynchronises the heart to pump blood more efficiently. This is called cardiac resynchronization therapy (CRT).
A CRT-P is a pacemaker, but like a mini computer that is specialised for managing heart failure. A pacemaker functions to replace the work of a persons heart’s natural pacemaker, the sinus node. With a pacemaker’s help, the heart can maintain a normal, healthy rhythm so it can circulate the amount of blood needed to meet the body’s need. A CRT-D is a type of specialized implantable cardioverter defibrillator (ICD) that manages heart failure by sending electrical impulses to synchronize the heart's chambers and sending an electrical shock to the heart if needed.
Physiologic pacing is a multi-centre, prospective registry and this registry will be conducted to gain a deeper understanding of the physiologic device implants and follow-up workflows, including device and programmer measurements to help inform Abbott’s product and clinical data development efforts.
The registry will include patients scheduled for implantation of an Abbott CRT pacemaker (CRT-P) or CRT defibrillator (CRT-D) and who meet all inclusion/exclusion criteria. Participants will be followed in-clinic at baseline (before implant), implant, and at 1 month and 6 months after the date of successful implant.REC name
West of Scotland REC 4
REC reference
20/WS/0171
Date of REC Opinion
13 Apr 2021
REC opinion
Further Information Favourable Opinion