PhysicalFnAfterICU
Research type
Research Study
Full title
Physical Function and Activity in Survivors of Critical Illness Following Discharge from the Intensive Care Unit (ICU): A Prospective Longitudinal Cohort Study
IRAS ID
216386
Contact name
Brenda O'Neill
Contact email
Sponsor organisation
Ulster University
Clinicaltrials.gov Identifier
IRAS Project ID, 216386
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
The aim of this study is to explore the changes in physical function and activity levels, inflammation and quality of life in survivors of critical illness following discharge from the Intensive Care Unit (ICU), over a one-year period. We will measure outcomes of physical function, activity, pain, quality of life, grip strength, psychosocial and inflammation at 4 different time points. A baseline assessment will be carried out prior to hospital discharge (or within two weeks)(T1), then subsequent assessments will be at 6 weeks +/- 2 weeks (T2) following hospital discharge, 6 months +/- 2 weeks (T3), 12 months +/- 2 weeks (T4). Patients' views will also be collected at baseline and at the final appointment to help provide information on patients’ perspectives of what factors influenced their progress after critical illness. Overall, this study will provide new information about the trajectory of recovery following critical illness and help to define a population(s) that might benefit from an intervention. It will help facilitate early identification of factors that could predict those at risk of poor physical and functional ability, as well as those who return to a healthy pattern of physical and functional ability after critical illness. It will help to determine outcome measures suitable for assessing the effectiveness of potential future rehabilitation interventions. This new information will contribute to improved patient outcomes, and will inform the design of future research involving patients who are recovering from critical illness.
REC name
HSC REC A
REC reference
17/NI/0057
Date of REC Opinion
3 Apr 2017
REC opinion
Unfavourable Opinion