Physical Activity Patterns After Knee Arthroplasty (PAPrKA)
Research type
Research Study
Full title
Physical Activity Patterns After Knee Arthroplasty (PAPrKA)
IRAS ID
333659
Contact name
William Dixon
Contact email
Sponsor organisation
University of Manchester
Duration of Study in the UK
1 years, 7 months, 31 days
Research summary
Knee replacement is a treatment option for end-stage knee osteoarthritis, used when non-invasive and drug-based therapy does not work. This treatment alleviates pain and improves mobility. Patients typically experience pain reduction within three months following surgery. Patients, however, have unanswered questions about the extent to which their physical activity (mobility) will improve long-term, whether they can regain their previous level of physical activity, and the expected pattern of recovery of activity post-operatively.
To address these questions, this retrospective study will leverage data from the National Joint Registry (NJR), consumer fitness trackers and brief questions asked in a survey. The study will recruit participants who meet these criteria: (a) live in England, Northern Ireland, Wales, the Isle of Man or Guernsey; (b) have knee osteoarthritis and had knee replacement surgery before December 2022; (c) used a fitness tracker pre- and post their knee replacement surgery. Potential participants will have to complete and submit electronic informed consent prior to providing the study with research data (physical activity data and survey responses). The collected data will be combined with participant’s knee replacement data in NJR. This dataset will be examined and analysed in de-identified form, on NJR's secure portal, using both descriptive statistics and statistical methods including latent class growth analysis and regression models.
Following the analysis of the data, the study is expected to generate insights into physical activity patterns before and after knee replacement surgery. The results will enable patients and clinicians to make more informed decisions before surgery: decisions based on anticipated future physical activity levels and an understanding of recovery patterns.
This study is funded by the University of Manchester and the University of Melbourne training research group and from UKRI’s Medical Research Council as part of the ‘Health Research from Home’ partnership grant.REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
24/NE/0090
Date of REC Opinion
22 May 2024
REC opinion
Favourable Opinion