Physical activity levels of FH patients and NICE guidelines
Research type
Research Study
Full title
Physical activity levels of FH patients and do they meet the current NICE recommendations?
IRAS ID
303529
Contact name
Jillian Webster
Contact email
Sponsor organisation
York St Johns University
Duration of Study in the UK
0 years, 11 months, 30 days
Research summary
Familial Hypercholesterolaemia (FH) is an inherited condition which leads to exceptionally high cholesterol levels, often double and sometimes four times those of the general population. One in 250 of the general population has FH but many are as yet undiagnosed, leaving individuals at high risk of developing cardiovascular disease and dying suddenly at a premature age from a heart attack. The aims of the study will be to establish what the current physical activity levels of FH patients are and do they currently meet the NICE recommendations. There are currently no targeted regimes for the FH population and this research would complement the provision of precision lifestyle and dietary advice to this group of people, enhancing the existing service and supplement current pharmaceutical therapies. Participants will be recruited from existing FH clinics in Huddersfield and Halifax Hospital outpatient departments. They will already have a genetic test result confirming FH and all participants will be 18 years old and over.
Blood lipid levels, age, weight, height, and waist circumference, blood pressure, smoking status, family history, personal history and medication will be recorded and collated during participant’s usual clinic visit. Physical activity will be recorded in two ways: Self-reported activity levels will be captured by the completion of an activity level questionnaire by the participant (International Physical Activity Questionnaire, IPAQ) Measurements of physical activity will be gained by using a recording device called an accelerometer. Data will be collected to show different levels of activity ranging from sedentary, low, moderate and high levels of intensity over a period of seven days.
Participants will be contacted via email or telephone about the study prior to their usual clinical appointment and provided with the participant information sheet to read. They will then attend their usual clinical appointment, where informed consent to participate in the study will be gained.REC name
London - Brighton & Sussex Research Ethics Committee
REC reference
22/PR/0780
Date of REC Opinion
20 Jul 2022
REC opinion
Further Information Favourable Opinion