Physical activity in patients with mild and moderate to severe asthma
Research type
Research Study
Full title
A Pilot study to assess physical activity and patient compliance with wrist and hip worn accelerometers in patients with mild and moderate to severe asthma
IRAS ID
262762
Contact name
S Dave Singh
Contact email
Sponsor organisation
Medicines Evaluation Unit Ltd
Duration of Study in the UK
0 years, 2 months, 31 days
Research summary
Asthma is a common chronic condition which can be mild to severe depending on the patient. Symptoms of asthma can lead to some patients becoming less active. Patient activity can be measured and recorded using small activity monitoring devices which can be worn in different places on the body. These devices monitor a patient’s day to day activity. The devices are most useful to capture information about activity when worn all the time. \nThe purpose of this study is to see if there are differences in activity level in patients who have worse asthma verses those with milder asthma and to look into the differences between an activity device worn on the wrist and one worn on the hip in patients with asthma.\n\nThis is a pilot study. 15 patients with mild and 15 patients with moderate to severe asthma will be enrolled. The study involves a minimum of 2 visits to the Medicines Evaluation Unit and two telephone calls. The study consists of a screening period of up to 2 weeks, and a 2-week period during which a wrist and hip accelerometer will be worn by each patient. Patients meeting eligibility criteria will be asked to wear both the hip and wrist accelerometers continuously for a 2-week study period except during battery charging periods, data uploads and bathing/swimming. Compliance will be evaluated over the study period through monitoring by a study centric web portal. The average number of steps walked, energy expenditure, duration of moderate-to-vigorous physical activity, duration of light to sedentary physical activity, number of hours accelerometers are worn per day or at night during sleep, and sleep duration and number of nocturnal awakening will be calculated over a 14-day period. These parameters will be compared between patient groups. Data obtained at the hip and wrist will be compared.
REC name
South Central - Oxford B Research Ethics Committee
REC reference
19/SC/0488
Date of REC Opinion
12 Sep 2019
REC opinion
Favourable Opinion