PH:fACTors influencing decisions about IV prostanoid therapy(PHACT-IV)
Research type
Research Study
Full title
What are the factors that influence decision making in adults with pulmonary hypertension offered intravenous prostanoid infusions?
IRAS ID
147678
Contact name
Margaret Lau-Walker
Contact email
Sponsor organisation
King's College University
Duration of Study in the UK
2 years, 0 months, 30 days
Research summary
The study is to investigate the factors that influence the decision when patients are offered treatment with intravenous prostanoid therapy.
This study will be in two parts: The first part of the study is to collect quantitative data: questionnaires (Perceived Social Support, Locus of Control, HADs, Decision Attitude Scale, EmPHasis-10 )will be sent out by post to all adult patients in the UK that are currently receiving IV prostanoid therapy. Their demographic data will be collected and there will be an opportunity for patients to add free text in a comments box.
The second part of the study is a prospective study of consecutive patients offered prostanoid infusions in a large nationally designated Pulmonary Hypertension Centre. They will be invited to take part in qualitative interviews to investigate in detail the factors that influence their decision making process, thereby collecting data from both patients that agree and those that refuse IV prostanoid therapy. Demographic data and the questionnaires used above will be collected for all study participants.
The quantitative data will be analysed using SPSS and the correlation between different factors investigated. The qualitative interviews will be transcribed and an analysed using an interpretive phenomenological approach to give in depth data. The quantitative data of patients that agree or refuse will be compared to investigate statistically significant differences.
The findings will provide information for healthcare professionals to gain a greater understanding of the factors that are important to patients. The results can be used to highlight factors that have the potential to be addressed to improve patient experience and provide support for patients in their decision.
REC name
London - Central Research Ethics Committee
REC reference
15/LO/0740
Date of REC Opinion
29 May 2015
REC opinion
Further Information Favourable Opinion