Phenotyping the Brecon Cohort: A Feasibility Study
Research type
Research Study
Full title
Phenotyping the Brecon Cohort of childhood-onset Type 1 Diabetes to identify those at risk of adverse long-term outcomes who may in future merit immunotherapeutic intervention at diagnosis: a feasibility study
IRAS ID
203706
Contact name
Sarah Dowrick
Contact email
Duration of Study in the UK
0 years, 6 months, 2 days
Research summary
Previous research has shown that children with Type 1 Diabetes (T1D) are at a 480% increased risk of hospital admission compared to children without T1D. This study plans to utilise the Brecon Cohort (a database of >97% of all children diagnosed with T1D in Wales) to conduct biological phenotyping of children with T1D to identify children who will benefit most from early immunotherapeutic intervention to preserve beta cell function.
This study will be a feasibility study to determine the optimal approach of recruiting children and young adults with T1D from the Brecon Cohort. It will also investigate the ease at which biological sampling can be conducted and which approach children and young adults prefer; clinic sampling, home sampling or a combination of the two.REC name
Wales REC 3
REC reference
16/WA/0200
Date of REC Opinion
30 Aug 2016
REC opinion
Further Information Favourable Opinion