PFT after KASS
Research type
Research Study
Full title
The long term effect of anterior scoliosis surgery on pulmonary function (PFT after KASS)
IRAS ID
171141
Contact name
Jwalant Mehta
Contact email
Sponsor organisation
The Royal Orthopaedic Hospital NHS Foundation Trust
Duration of Study in the UK
0 years, 10 months, 1 days
Research summary
Lay title: The long term effect of scoliosis surgery on lung function
Background: Review of evidence suggests that lung capacity in some scoliosis patients may not be normal before surgery, and that operating through the chest (i.e. anterior surgery) may have a further negative impact on the lung function. Reduced lung capacity after anterior scoliosis surgery may result in limitations to daily activities due to increased work of breathing at rest, during exercise and sleep. Though such detrimental impact is likely to be moderate and affect only some patients, we need to know more about the long-term impact of anterior scoliosis surgery. Therefore it is important to follow up scoliosis patients after anterior surgery for long-term health outcomes.
Purpose: The purpose of the study is to assess the long-term health outcomes of anterior scoliosis surgery by investigating lung function and self-reported health in patients who underwent this type of surgery between 2000 and 2006 at the Royal Orthopaedic Hospital in Birmingham. The length of the follow-up is up to 15 years.
Methods: Fifty-four patients who underwent anterior scoliosis surgery at the Royal Orthopaedic Hospital will be recruited to take part in this study. The study participants will be asked to attend the spinal outpatient clinic at ROH to undergo lung function tests and to complete three questionnaires that measure physical function and health-related quality of life. We will compare lung function before and up to 15 years after the surgery and assess the relationship between lung function, the questionnaire scores, and information from medical records
Outcomes: Based on the results, recommendations will be made concerning long-term routine follow-up and care at ROH and other specialist spinal surgery units.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
15/NE/0246
Date of REC Opinion
5 Aug 2015
REC opinion
Further Information Favourable Opinion