Perspectives on CPPD outcome domains
Research type
Research Study
Full title
OMERACT core domain set selection for Calcium Pyrophosphate Deposition (CPPD): exploring patient and stakeholder perspectives on outcome domains
IRAS ID
268693
Contact name
A Abhishek
Contact email
Sponsor organisation
University of Nottingham
Clinicaltrials.gov Identifier
NA, NA
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
The purpose of this study is to obtain patient and stakeholder perspectives on what outcome measures should be included in future trials on CPPD (Calcium PyroPhosphate Deposition), a common form of inflammatory arthritis.
This will form part of a wider OMERACT (Outcome Measures in Rheumatology) study, involving multiple international sites, to determine a core domain set (an agreed set of outcome measures) for this disease.
In the UK, patients with CPPD and their caregivers, healthcare professionals who care for patients with CPPD, and other stakeholders, which may include government organisations, non-government organisations, pharmaceutical representatives and health advocacy groups, will be invited to participate in a single, semi-structured interview.
Interviews will be face-to-face or telephone, last up to one hour and digitally audio-recorded. For patients and their caregivers, interviews will explore their lived experience of CPPD, its impact on their daily lives, and the perceived relevance of outcome measures used in previous studies. For healthcare professionals and other stakeholders, interviews will explore their experience dealing with patients with CPPD, how they perceive CPPD impacts patient lives, and the perceived relevance of the outcome measures used in previous studies.
Following analysis of the data, participants will be sent a short report with the researchers’ findings, and asked to check the accuracy of these and provide brief written feedback.Interviews will also take place with patients, caregivers, healthcare practitioners and stakeholders at the other international sites where ethics committee approval will be sought locally. Analysis of all interviews will be primarily conducted and managed at the UK site.
REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
19/WM/0264
Date of REC Opinion
9 Sep 2019
REC opinion
Further Information Favourable Opinion