Peri-adventitial SMA dissection during pancreaticoduodenectomy
Research type
Research Study
Full title
Effect of peri-adventitial SMA dissection on margin status during pancreaticoduodenectomy for resectable pancreatic cancer
IRAS ID
265878
Contact name
Nikolaos Chatzizacharias
Contact email
Sponsor organisation
University Hospitals of Birmingham NHS Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 11 months, 31 days
Research summary
The incidence of microscopic residual cancer after pancreatic resection for pancreatic cancer is very variable. Unfortunately, there are clear evidences that a non-radical resection (R1) is affecting the survival rate in patients affected by pancreatic cancer. It is believed that the peri-adventitial surgical approach proposed in this study could decrease the rate of microscopical residual tumor and increase survival. However, there are lack of experimental studies comparing this technique with a standard surgical approach. This research will aim to investigate the role of routine peri-adventitial dissection on the margin status and local recurrence rates.
REC name
North West - Liverpool Central Research Ethics Committee
REC reference
20/NW/0182
Date of REC Opinion
13 May 2020
REC opinion
Further Information Favourable Opinion