Perfusion MRI in reversible cerebral vasoconstriction syndrome
Research type
Research Study
Full title
Perfusion MRI in reversible cerebral vasoconstriction syndrome
IRAS ID
183791
Contact name
Nikos Evangelou
Contact email
Duration of Study in the UK
1 years, 5 months, 31 days
Research summary
Reversible Cerebral Vasoconstriction Syndrome (RCVS) is a group of conditions characterised by prolonged but typically temporary narrowing of certain blood vessels in the brain. It may cause people to have headache or occasionally other more serious symptoms. The diagnosis of RCVS is made by a brain scan, but there are occasions when this is not enough due to the timing of scan or the technique used.
The purpose of this study is to assess whether new Magnetic Resonance Imaging (MRI) scans can help diagnose and improve our understanding of RCVS. The University of Nottingham has a specialised MRI scanner that lets us get very high-resolution images. We want to use this scanner to measure the narrowing of blood vessels and the amount of blood flowing into the brain in patients that may have RCVS, to help confirm diagnosis. We will also repeat the scans at 1 month and at 3 months to determine how the blood vessels and blood flow change over time.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
15/WM/0372
Date of REC Opinion
23 Oct 2015
REC opinion
Favourable Opinion