PBAF and genome stability in renal cell carcinoma

• Research type

  Research Study

• Full title

  Analysis of the contribution of PBAF to genome stability in renal cell carcinoma

• IRAS ID

  167407

• Contact name

  Duncan Gilbert

• Contact email

  duncan.gilbert@bsuh.nhs.uk

• Sponsor organisation

  Brighton and Sussex University Hospitals NHS Trust

• Duration of Study in the UK

  1 years, 3 months, 29 days

• Research summary

  Renal cell cancers have a frequently occurring gene mutation that impairs their ability to repair DNA promoting further changes that drives the cancer. We want to characterise this in a group of renal cancer specimens to better understand the underlying biological mechanisms and any implications for future treatments.

• REC name

  North West - Liverpool Central Research Ethics Committee

• REC reference

  15/NW/0057

• Date of REC Opinion

  14 Jan 2015

• REC opinion

  Favourable Opinion