PATTErn Study
Research type
Research Study
Full title
A study of Physical Activity paTTerns and major health Events in older people with implantable cardiac devices (PATTErn)
IRAS ID
215964
Contact name
Adam Greenstein
Contact email
Sponsor organisation
Univeristy of Manchester
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Summary of Research
The PATTErn study aims to utilise routinely collected data from cardiac device downloads to improve our understanding of the relationship between physical activity (PA), frailty and major health events in an older population with heart disease.
Clinical practice would suggest that older people tend to experience a decline in PA preceding periods of ill-health, particularly those living with long term conditions or frailty. This raises the possibility that PA could be used as a time-sensitive marker of health status. PA monitoring using technological devices could be used as a future management strategy, guiding the need for intervention before a patient requires hospitalisation.
In order to develop such systems, we need to understand the ‘normal’ day-to-day patterns of PA, and how PA changes surrounding periods of ill-health. This need is best met by real-world, observational data. Most modern implantable cardiac devices (CIEDs) contain an accelerometer that measures daily PA (a calculation made from daily step count). Devices store this data for up to 14 months, and can be easily downloaded at any time using a wireless device. This routinely collected data offers a unique opportunity to study PA patterns.
The PATTErn study will recruit 150 people aged ≥60 years with CIEDs in situ from the Manchester University NHS Foundation Trust (Manchester Royal Infirmary and Wythenshawe hospital sites) over an 18-month period. Participants will be recruited from routine outpatient device clinics. Participants will be asked to complete a questionnaire, perform some basic functional assessments and allow us to collect an extra copy of their device download data. This new, observational data will be analysed to explore PA patterns, correlations with frailty and general health status, and the temporal relationship between PA and major health events (as measured by non-elective hospital attendance episodes).
Summary of Results
: Physical activity from older people with cardiac devices was shown to associate with measures of clinical frailty and physical functioning. On physical activity trajectory analysis, "steady", "peaked" and "dipped" morphologies were identified.
REC name
London - Bromley Research Ethics Committee
REC reference
18/LO/1055
Date of REC Opinion
15 Jun 2018
REC opinion
Favourable Opinion